Viral metagenomics reveals diverse viruses in the fecal samples of children with acute respiratory infection.

ABSTRACT:

Introduction

Changes in the gut microbiome have been associated with the development of acute respiratory infection (ARI). However, due to methodological limitations, our knowledge of the gut virome in patients with ARIs remains limited.

Methods

In this study, fecal samples from children with ARI were investigated using viral metagenomics.

Results

The fecal virome was analyzed, and several suspected disease-causing viruses were identified. The five viral families with the highest abundance of sequence reads were Podoviridae, Virgaviridae, Siphoviridae, Microviridae, and Myoviridae. Additionally, human adenovirus, human bocavirus, human astrovirus, norovirus, and human rhinovirus were detected. The genome sequences of these viruses we

SUBMITTER: Xu P 

PROVIDER: S-EPMC12009832 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature