Global trends in antimicrobial resistance of <i>Enterococcus faecium</i>: a systematic review and meta-analysis of clinical isolates.

ABSTRACT:

Background

Multidrug-resistant bacteria are associated with a high number of deaths and pose a significant global concern. In recent decades, among these resistant bacteria, Enterococcus faecium, a hospital-acquired pathogen, has attracted more attention.

Objective

The present study aims to document the current state of resistance in E. faecium globally by considering several variables, including geographical locations, temporal trends, and sources of infection.

Methods

We searched studies in PubMed, Scopus, and Web of Science (30 November 2022). All statistical analyses were carried out using the statistical package R.

Results

Our meta-analysis of antibiotic resistance across various clinical isolates revealed substantial heterogeneity and variab

SUBMITTER: Huang C 

PROVIDER: S-EPMC12009923 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature