Involvement of common risk factors in the associations between lifetime unemployment exposure, major health outcomes and mortality: a retrospective and prospective study in a large population-based French cohort.

ABSTRACT:

Objectives

Uncertainty exists as to what extent common risk factors are involved in the associations of unemployment with major health outcomes and mortality.

Design

A retrospective and prospective observational study.

Setting

A large population-based French cohort (CONSTANCES).

Participants

99 430 adults at baseline who have been exposed to unemployment during their lifetime and 54 679 of them who were followed for 7 years after baseline.

Primary outcome measures

Testing the mediating roles of several risk factors at baseline in the associations of lifetime unemployment exposure with cardiovascular disease, cancer and mortality rates during a 7-year follow-up. Direct and indirect effects were calculated for each risk factor and all together using logist

SUBMITTER: Sanchez Rico M 

PROVIDER: S-EPMC12010334 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature