Association of weight-adjusted waist index with all-cause and cardiovascular mortality in individuals with osteoarthritis.

ABSTRACT:

Background

The Weight-Adjusted waist index (WWI) is a novel obesity assessment parameter that has been shown to be associated with mortality in various chronic disease populations and is also linked to the onset of osteoarthritis (OA). The aim of this study is to investigate whether WWI is associated with all-cause and cardiovascular mortality in OA population.

Methods

The study analyzed a cohort of 3,554 OA patients drawn from the National Health and Nutrition Examination Survey (NHANES) conducted between 2005 and 2018. Kaplan-Meier survival curves, Cox proportional hazards regression models, and subgroup analyses were utilized to assess the association between WWI and mortality outcomes. The dose-response relationship was examined using a restricted cubic spline (RCS) mode

SUBMITTER: Guo S 

PROVIDER: S-EPMC12010517 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature