The relationship between the eradication of Helicobacter pylori and the occurrence of stomach cancer: an updated meta-analysis and systemic review.

ABSTRACT:

Objective

Helicobacter pylori (H. pylori) are classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC), highlighting its well-established role in gastric carcinogenesis. While previous studies and systematic reviews suggest that H. pylori eradication may lower the incidence and mortality of gastric cancer, the evolving body of evidence necessitates continual reassessment. In light of newly available data, we conducted a comprehensive meta-analysis to evaluate the association between H. pylori eradication therapy and gastric cancer risk, aiming to strengthen the evidence base and inform clinical decision-making.

Method

We systematically searched the Cochrane Library, PubMed, Web of Science, and Embase up to December 2024, including only ran

SUBMITTER: Wu Z 

PROVIDER: S-EPMC12010618 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature