Association of mean corpuscular volume with 28-day mortality in sepsis patients: A retrospective cohort study using eICU data.

ABSTRACT:

Introduction

The issue of mortality due to sepsis remains a significant concern in the field of medicine. Previous researches have demonstrated an association between mean corpuscular volume (MCV) and mortality from a range of diseases. The objective of this study was to investigate the relationship between MCV and the risk of mortality from sepsis in a large multicentre cohort.

Method

A retrospective cohort study was conducted using data from the eICU Collaborative Research Database from 2014-2015. MCV was determined within the initial 24 hours of ICU admission, with patients subsequently classified into quartiles based on their MCV levels. Multivariate regression models were employed to investigate the correlation between MCV and 28-day mortality, with adjustments made for

SUBMITTER: Tang H 

PROVIDER: S-EPMC12011257 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature