Comparison of widefield swept-source optical coherence tomography angiography and ultra-widefield fluorescein angiography in the detection of non-perfusion areas in diabetic retinopathy.

ABSTRACT:

Purpose

To compare the detection of non-perfusion areas (NPAs) in diabetic retinopathy (DR) using 24×20 mm widefield swept-source optical coherence tomography angiography (SS-OCTA) and ultra-widefield fluorescein angiography (UWFA), and to explore NPA distribution patterns.

Methods

This retrospective study included 64 eyes from 48 DR patients who underwent 24×20 mm SS-OCTA and UWFA examinations. NPAs were manually annotated, and the detection rates and distribution patterns across retinal quadrants were analyzed and compared between the two imaging modalities.

Results

Compared to UWFA, the 24×20 mm SS-OCTA scan range missed 53.40% of total NPAs. The detection rates within the SS-OCTA scan range varied across quadrants: 50.58% (superior temporal), 55.33% (inferior temp

SUBMITTER: Guo C 

PROVIDER: S-EPMC12011578 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature