Triglyceride-glucose index and prognosis in non-diabetic critically ill patients: data from the eICU database.

ABSTRACT:

Background

The triglyceride-glucose (TyG) index is a marker for insulin resistance (IR) linked to diabetes complications and poor outcomes. Its connection to all-cause mortality in non-diabetic critically ill patients is unknown. This study aims to investigate the TyG index's impact on mortality in this population, evaluating how IR affects their prognosis.

Methods

This study is retrospective observational research utilizing data from the eICU Collaborative Research Database. A total of 14,089 non-diabetic critically ill patients were included and categorized into three groups based on the TyG index measured on the first day of admission (T1, T2, and T3). Kaplan-Meier survival analysis was performed to compare the 28-day mortality rates among the different groups. Cox propor

SUBMITTER: Li X 

PROVIDER: S-EPMC12011771 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature