Four-dimensional flow magnetic resonance assessment of alcohol septal ablation for hypertrophic obstructive cardiomyopathy and surgical valve replacement for aortic valve stenosis.

ABSTRACT:

Background

Hypertrophic cardiomyopathy sometimes complicates left ventricular (LV) outflow tract obstruction. Alcohol septal ablation (ASA) is indicated for drug-refractory hypertrophic obstructive cardiomyopathy (HOCM). Moreover, with an aging population, aortic valve stenosis (AS) is increasing, and surgical aortic valve replacement (SAVR) is indicated in these cases. Both AS and HOCM have stenosis at the exit of the LV and there is a difference in valvular and/or muscular stenosis. However, it is not clear how the release of stenosis affects blood flow. We investigate the influence of ASA and SAVR on blood flow using four-dimensional flow phase-contrast magnetic resonance imaging (4D flow MRI).

Methods

In this single-center retrospective observational study, we evaluated

SUBMITTER: Aoyama R 

PROVIDER: S-EPMC12011773 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature