Second primary cancers among males with a first primary prostate cancer: a population-based study in Northern Portugal.

ABSTRACT: Increased survival and life expectancy among patients with prostate cancer results in an increased risk of developing a second primary cancer (SPC). We aimed to describe the occurrence of SPCs in a population-based cohort with a prostate first primary cancer (FPC), in Northern Portugal. A cohort of 13,222 patients with a prostate FPC from the North Region Cancer Registry of Portugal, diagnosed between 2000 and 2009, was followed until 31 December 2021, for synchronous (within six months of FPC diagnosis) and metachronous SPCs (all others). We describe absolute and relative frequencies of SPCs, incidence rates and standardized incidence ratios of SPCs (compared to the male general population), and cumulative incidence of metachronous SPCs. A total of 1953 (14.8%) patients with a prostate FP

SUBMITTER: Taveira-Barbosa J 

PROVIDER: S-EPMC12011927 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature