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Association between the (neutrophil + monocyte)/albumin ratio and all-cause mortality in sepsis patients: a retrospective cohort study and predictive model establishment according to machine learning.


ABSTRACT:

Introduction

Sepsis is a life-threatening condition characterized by widespread inflammatory response syndrome in the body resulting from infection. Previous studies have demonstrated that some inflammatory factors or nutritional elements contributed to deaths in patients diagnosed with sepsis. Nevertheless, the correlation between the (neutrophil + monocyte)/albumin (NMa) ratio and all-cause mortality of patients diagnosed with sepsis remains unclear. This study aims to investigate the association between the NMa ratio and all-cause mortality in sepsis patients and to develop a predictive model using machine learning techniques.

Methods

The clinical data were harvested from 13,851 patients with sepsis from the MIMIC-IV (3.1) database. We divided the subjects into four group

SUBMITTER: Liu L 

PROVIDER: S-EPMC12012944 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature