Comparative chemical and antimicrobial evaluation of the essential oils from Callistemon and podocarpus species supported by in-silico molecular simulations against bacterial LacY protease.

ABSTRACT:

Background

Myrtaceae and Podocarpaceae botanical families include several aromatic species that have been proven to have diverse pharmacological potential, especially antimicrobial effects. Additionally, plants of both families were reported for their benefits in traditional medicine. The current study demonstrated the chemical profile, antimicrobial of four investigated plant species (C. subulatus, C. rigidus, P. gracilior, and P. elongatus) leaves cultivated in the same place in Egypt and propose in-silico modeling for the antibacterial mechanistic action.

Method

The essential oils samples were prepared via hydrodistillation and headspace extraction protocol and GC analysis was conducted to obtain a comparative chemical profile. The antimicrobial activity of the obtained h

SUBMITTER: Ezzat HAM 

PROVIDER: S-EPMC12012950 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature