Predicting Cow's Milk Challenge Outcomes in Children: Multivariate Analysis of Clinical Predictors.

ABSTRACT:

Introduction

Oral food challenges are the gold standard for diagnosis and reactivity thresholds but are resource intensive and high risk for reactions. Limited data on factors associated with increased risk of positive oral food challenges exist. We aimed to assess factors associated with positive oral food challenges and create a model to predict cow milk oral food challenge outcomes.

Methods

Children aged 5-18 being considered for cow's milk oral immunotherapy underwent a single-blind, placebo-controlled food challenge to cow's milk, with either positive (reaction) or negative (tolerance) outcomes. Initial factors recorded included sex, age, history of asthma, eczema, allergic rhinitis, prior epinephrine use for cow's milk-induced reactions, skin prick test size, serum lev

SUBMITTER: Delli Colli L 

PROVIDER: S-EPMC12013213 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature