Open reading frames provide a rich pool of potential natural antisense transcripts in fungal genomes.

ABSTRACT: Natural antisense transcripts are reported from all kingdoms of life and several recent reports of genomewide screens indicate that they are widely distributed. These transcripts seem to be involved in various biological functions and may govern the expression of their respective sense partner. Very little, however, is known about the degree of evolutionary conservation of antisense transcripts. Furthermore, none of the earlier analyses has studied whether antisense relationships are solely dual or involved in more complex relationships. Here we present a systematic screen for cis- and trans-located antisense transcripts based on open reading frames (ORFs) from five fungal species. The relative number of ORFs involved in antisense relationships varies greatly between the five species. In a

SUBMITTER: Steigele S 

PROVIDER: S-EPMC1201330 | biostudies-literature | 2005

REPOSITORIES: biostudies-literature