Empirical evidence of predictive adaptive response in humans: systematic review and meta-analysis of migrant populations.

ABSTRACT: Meta-analysis is used to test a variant of a Developmental Origins of Adult Health and Disease (DOHaD)'s conjecture known as predictive adaptive response (PAR). According to it, individuals who are exposed to mismatches between adverse or constrained in utero conditions, on the one hand, and postnatal obesogenic environments, on the other, are at higher risk of developing adult chronic conditions, including obesity, type 2 diabetes (T2D), hypertension and cardiovascular disease. We argue that migrant populations from low and middle to high-income countries offer a unique opportunity to test the conjecture. A database was constructed from an exhaustive literature search of peer-reviewed papers published prior to May 2021 contained in PUBMED and SCOPUS using keywords related to migran

SUBMITTER: Bueno Lopez C 

PROVIDER: S-EPMC12013326 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature