Clinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer Progression: A Randomized Trial.

ABSTRACT:

Importance

Historically, fewer than 10% of adults with cancer have enrolled in clinical trials. Computational tools have been developed to match patients to trials, but these tools are relevant only when patients need new treatment.

Objective

To evaluate whether notifying oncologists about genomically targeted clinical trials for patients with cancer progression, as detected by artificial intelligence (AI), impacts clinical trial participation.

Design, setting, and participants

This single-center randomized trial was conducted from January 30, 2023, to June 30, 2024, at a tertiary academic cancer center. Participants were patients aged at least 18 years in a precision oncology clinical trial matching database who had solid tumors that underwent next-generation sequenc

SUBMITTER: Mazor T 

PROVIDER: S-EPMC12013351 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature