Evaluation of a new classification system for measuring the progression of ocular cystinosis: an analysis of 64 patients.

ABSTRACT:

Aims

To analyse the correlation between the physician categories defined by the 3C classification (crystal-complication-compliance) and the ocular manifestations of nephropathic cystinosis.

Methods

The last visit data of 64 patients aged between 2 and 64 attending the centre for management of cystinosis were reviewed. Each patient had been placed into one of four categories by the clinician based on disease severity. The correlation between these categories and markers of the disease was assessed using Pearson's correlation.

Results

Photophobia (0.647, p<0.001), visual acuity (-0.695, p<0.001), Gahl's score (0.603, p<0.001), optical coherence tomography (OCT)% (0.713, p<0.001) and in vivo confocal microscopy (IVCM)% (0.845, p<0.001), showed a strong, highly significan

SUBMITTER: Liang H 

PROVIDER: S-EPMC12013570 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature