Effect of different origins on genes encoding key enzymes involved in the polysaccharide biosynthetic pathway in Hedysarum polybotrys Hand.-Mazz.

ABSTRACT: Radix Hedysari (HP) is a traditional Chinese medicine that has gained widespread attention for its tonic effects. Environmental factors significantly influence the active components in HP, notably Radix Hedysari polysaccharides (HPS), which are the principal active constituents. To date, no studies have reported on the environmental impact on the accumulation and biosynthesis of HPS. This research aims to evaluate the HPS accumulation and its biosynthetic pathways across different environments. We measured the HPS levels in samples from the core geographic area (geo-authentic product region) in Wudu, Gansu Province (WD), and a non-core geographic area (non-geo-authentic product region) in Tanchang, Gansu Province (TC), and conducted transcriptomic analyses. The HPS content in HP from WD (H

SUBMITTER: Wang ZX 

PROVIDER: S-EPMC12013888 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature