Development of a complex multidisciplinary medication review and deprescribing intervention in primary care for older people living with frailty and polypharmacy.

ABSTRACT:

Introduction

Reducing polypharmacy and overprescribing in older people living with frailty is challenging. Evidence suggests that this could be facilitated by structured medication review (SMR) and deprescribing processes involving the multidisciplinary team (MDT). This study aimed to develop an MDT SMR and deprescribing intervention in primary care for older people living with frailty.

Methods

Intervention development was informed by the Medical Research Council framework for complex intervention and behaviour change and implementation theories. Intervention planning included: 1) a realist review of 28 papers that identified 33 context-mechanism-outcome configurations for successful MDT SMR and deprescribing in primary care, 2) a qualitative study with 26 healthcare profess

SUBMITTER: Radcliffe E 

PROVIDER: S-EPMC12013936 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature