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Nonbacterial Thrombotic Endocarditis of the Aortic Valve in a Patient With Antiphospholipid Syndrome.


ABSTRACT: A 41-year-old woman presented with new-onset heart failure and severe aortic valve thickening and stenosis. Persistent negative cultures and multimodality cardiac imaging revealed a nonbacterial thrombotic endocarditis. Later, positive antiphospholipid antibodies and tissue biopsy confirmed a nonbacterial thrombotic endocarditis related to antiphospholipid syndrome. Aortic surgical repair was successfully performed.

SUBMITTER: Gonzalez C 

PROVIDER: S-EPMC12014292 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature

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Nonbacterial Thrombotic Endocarditis of the Aortic Valve in a Patient With Antiphospholipid Syndrome.

Gonzalez Carlos C   Salido Mario M   Fernandez Juan J   Rodriguez Alvaro A   Duran Albert A   López Laura L   López Laura L   Sionis Alessandro A   Viladés David D   Descalzo Martín M  

JACC. Case reports 20250122 6 Pt 2


A 41-year-old woman presented with new-onset heart failure and severe aortic valve thickening and stenosis. Persistent negative cultures and multimodality cardiac imaging revealed a nonbacterial thrombotic endocarditis. Later, positive antiphospholipid antibodies and tissue biopsy confirmed a nonbacterial thrombotic endocarditis related to antiphospholipid syndrome. Aortic surgical repair was successfully performed. ...[more]

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