Contemporary Management of Severe Carcinoid Heart Disease.

ABSTRACT:

Background

Carcinoid heart disease (CHD), despite its rarity, is a serious complication of carcinoid syndrome (CS). Approximately 50% of patients with CS will develop CHD during the course of their disease. It predominantly affects the right-sided heart valves, leading to valve defect and right heart failure. In patients with advanced functional neuroendocrine tumors, diagnosing and managing CHD remains a challenge.

Case summary

A 71-year-old male with a metastatic midgut neuroendocrine tumor and CS presented with worsening right heart failure. Despite initiating treatment appropriately, he deteriorated and ultimately died, highlighting the difficulty of CHD management in advanced cases.

Review summary

Early detection and prompt management of CS are vital to prevent t

SUBMITTER: Mano Geran S 

PROVIDER: S-EPMC12014328 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature