Formula with large, milk phospholipid-coated lipid droplets in late-moderate preterm infants: a double-blind RCT.

ABSTRACT:

Background

Limited evidence exists on the preferred feeding method when breastfeeding is not possible in late and moderate preterm (LMPT) infants. This RCT evaluates growth, safety, and tolerance of a concept infant formula (IF) with large, milk phospholipid-coated lipid droplets enriched in dairy lipids in LMPT infants with primary objective to demonstrate non-inferiority of daily weight gain from randomization to 3 months corrected age compared to a standard IF.

Methods

LMPT infants were randomized before or around term equivalent age to either the concept (n = 21) or standard IF (n = 20). Forty-one breastfed (BF) infants served as reference.

Results

Due to unintended low recruitment, non-inferiority in daily weight gain could not be demonstrated for the Concept com

SUBMITTER: Kakaroukas A 

PROVIDER: S-EPMC12014481 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature