Elevated concentrations of methyl isocyanate and isocyanic acid in cigarette smoke.

ABSTRACT: Monoisocyanates are usually intermediates of industrial processes but alkyl-isocyanates and isocyanic acid can also be created when nitrogen-containing compounds thermally degrade. One of the most notable monoisocyanates, methyl isocyanate (MIC), was accidentally released to the surrounding from a pesticide plant in the Bhopal disaster of 1984, where it killed several thousand and injured many more (Mishra et al. Int J Occup Med Environ Health 22(3):193-202 2009). MIC is known to have adverse effects on the respiratory system and other mucous membranes. Links between cigarette smoking and exposure to monoisocyanates have been suggested but not properly evaluated. The aim of the present study was to measure isocyanates in direct smoke and exhaled smoke to determine the potential exposure fo

SUBMITTER: Runstrom Eden G 

PROVIDER: S-EPMC12014798 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature