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The role of the circadian timing system in sarcopenia in old age: a scoping review.


ABSTRACT:

Purpose

Sarcopenia is a progressive and generalized skeletal muscle disorder, involving the accelerated loss of skeletal muscle mass and function, associated with an increased probability of adverse outcomes including falls. The circadian timing system may be involved in molecular pathways leading to sarcopenia in older adults. We aimed to provide an updated and systematic map of the available evidence on the role of the circadian timing system in sarcopenia, specifically related to the aging process.

Methods

We developed a scoping review protocol following the PRISMA-ScR guidelines. Searches were conducted on PubMed, Scopus, Web of Science, RESULTS: We identified 373 papers from three online databases, screened 97 for full-text analysis. and selected 37 papers for inclusion

SUBMITTER: Palmese F 

PROVIDER: S-EPMC12014836 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature