Ictal scalp EEG patterns are shaped by seizure etiology in temporal lobe epilepsy.

ABSTRACT:

Objective

To investigate how etiology and seizure localization influence ictal scalp electroencephalographic (EEG) patterns in temporal lobe epilepsy (TLE).

Methods

We retrospectively analyzed ictal EEG features from 504 focal seizures recorded in 189 TLE patients with various etiologies who underwent resective surgery.

Results

For seizure onset patterns (SOPs), α/β onset was more common in the low-grade tumor group (38.4%) than in the hippocampal sclerosis (HS) group (14.1%, p < 0.001). The ictal EEG duration was shorter in the tumor group compared to the focal cortical dysplasia (FCD), HS, and non-specific groups (p < 0.05). Among mesial TLE patients, SOPs varied depending on the etiology. Within both the tumor and non-specific groups, SOPs and the spreading time to

SUBMITTER: Xu S 

PROVIDER: S-EPMC12014931 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature