Beyond traditional therapies: a network meta-analysis on the treatment efficacy for chronic phantom limb pain.

ABSTRACT:

Background

Phantom limb pain (PLP) frequently affects individuals with limb amputations. When PLP evolves into its chronic phase, known as chronic PLP, traditional therapies often fall short in providing sufficient relief. The optimal intervention for chronic PLP remains unclear.

Objective

The objectives of this network meta-analysis (NMA) were to examine the efficacy of different treatments on pain intensity for patients with chronic PLP.

Evidence review

We searched Medline, EMBASE, Cochrane CENTRAL, Scopus, and CINAHL EBSCO, focusing on randomized controlled trials (RCTs) that evaluated interventions such as neuromodulation, neural block, pharmacological methods, and alternative treatments. An NMA was conducted based on the Preferred Reporting Items for Systematic R

SUBMITTER: Chung SM 

PROVIDER: S-EPMC12015063 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature