Cognitive performance in young adult women with a history of premature adrenarche.

ABSTRACT:

Background

Girls with premature adrenarche (PA) mature earlier than peers and have been found to have greater symptom accounts reflecting anxiety compared to peers. It is not known, however, whether PA effects cognitive development. This longitudinal case-control cohort study aimed: (1) To investigate whether a history of PA leads to measurable changes in adulthood cognitive performance, and (2) to assess whether findings characteristic of PA girls predict adulthood cognitive performance.

Methods

Twenty-seven girls with PA and 27 age-matched control girls were examined and followed from mid-childhood (mean age 7.2 years) until early adult age (18.5 years). Wechsler Adult Intelligence Scale, Fourth Edition scores were used as main outcome measure.

Results

Allostatic lo

SUBMITTER: Tennila J 

PROVIDER: S-EPMC12015106 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature