Exploring the mechanisms of Chaige Kangyi Recipe in treating recurrent pregnancy loss with insulin resistance.

ABSTRACT: Chinese herbal medicine effectively treats recurrent pregnancy loss, though its mechanism is unclear. This study used RStudio 4.3.0 to collect successful cases for cluster analysis, identifying medication patterns and core formulas, and further researching key prescriptions. The prescription is frequently used for recurrent abortion patients with insulin resistance. UPLC-QTOF-MS identified components, and network pharmacology explored key prescription targets in recurrent abortion with insulin resistance, validated by molecular docking and in vitro experiments. Traditional Chinese medicine treatment for 177 recurrent abortion cases and 640 prescriptions was analysed using RStudio 4.3.0 to identify medication patterns. Chaige Kangyi Recipe (CGKYR) active components and targets were obtained

SUBMITTER: Wu J 

PROVIDER: S-EPMC12015438 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature