<i>Staphylococcus aureus</i> colonization and surgical site infections among patients undergoing surgical fixation for acute fractures.

ABSTRACT:

Objectives

To identify risk factors for methicillin-susceptible (MSSA) and methicillin-resistant S. aureus (MRSA) nasal carriage and surgical site infection (SSI) among patients undergoing fracture fixation procedures who were included in a quality improvement protocol involving screening patients for S. aureus nasal carriage and treating carriers with intranasal mupirocin and chlorhexidine bathing.

Design

Retrospective cohort study.

Setting

Level 1 trauma center.

Participants

1,254 adults who underwent operative fixation of 1,298 extremity or pelvis fractures between 8/1/2014 - 7/31/2017.

Methods

We calculated rates of S. aureus nasal carriage and SSI. We used multivariable stepwise logistic regression and selected the final models

SUBMITTER: Ahmann M 

PROVIDER: S-EPMC12015622 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature