Childhood Exposure to Air Pollution, Body Mass Index Trajectories, and Insulin Resistance Among Young Adults.

ABSTRACT:

Importance

Emerging evidence suggests that exposure to air pollution affects children's glucose metabolism. However, the underlying mechanisms are not fully understood.

Objective

To investigate whether body mass index (BMI; calculated as the weight in kilograms divided by the height in meters squared) growth trajectories mediate the association between traffic-related air pollution (TRAP) and insulin resistance.

Design, setting, and participants

As part of the Southern California Children's Health Study, the ongoing Meta-Air2 cohort substudy followed up participants from pregnancy to 24 years of age and examined the mediation role of BMI. Cardiometabolic follow-up was initiated as participants transitioned into adulthood. Data from the Meta-Air2 substudy were collecte

SUBMITTER: Guo F 

PROVIDER: S-EPMC12015664 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature