C-reactive protein in the first 30 postoperative days and its discriminative value as a marker for postoperative infections, a multicentre cohort study.

ABSTRACT:

Objective

To assess the association of C-reactive protein (CRP) with postoperative infections for eight different types of surgery using big data.

Design

A multicentre cohort study with longitudinally collected data from electronic health records, collected from 1 January 2011 to 22 September 2023.

Setting

Data of two tertiary medical centres in the Netherlands were used.

Participants

This study included all procedures (42 125 in total) in adult patients undergoing surgery in two tertiary medical centres in the Netherlands.

Outcome measures

The primary outcome was the association between CRP and a postoperative infection in the first 30 days postoperatively. Postoperative infection was defined by an action-based definition, that is, patients had to be tr

SUBMITTER: van Boekel AM 

PROVIDER: S-EPMC12015726 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature