Providencia pseudovermicola sp. nov.: redefining Providencia vermicola and unveiling multidrug-resistant strains from diabetic foot ulcers in Egypt.

ABSTRACT:

Background

Providencia species are concerning due to their intrinsic resistance to colistin and tigecycline, complicating the treatment of multidrug-resistant (MDR) infections.

Methods

In the current study, two MDR isolates, DFU6 and DFU52^T, were recovered from infected diabetic foot ulcers in Egypt in 2024. Following their initial identification as Providencia stuartii using VITEK® 2 and MALDI-TOF-MS, the isolates were subjected to whole-genome sequencing via DNBseq.

Results

While the 16S rRNA gene showed 100% similarity to that of Providencia vermicola, phylogenomic analysis against the type strains in the TYGS database, including P. vermicola DSM 17385^T confirmed that these isolates represent a distinct species within the genus, further suppor

SUBMITTER: Hamed SM 

PROVIDER: S-EPMC12016157 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature