Association between social determinants of health with the all-cause and cause-specific (cancer and cardio-cerebrovascular) mortality among the population with metabolic syndrome: NHANES 2005-2018.

ABSTRACT:

Background

Social determinants of health (SDOH) and metabolic syndrome (MetS) are related, but their combined effect on mortality risk remains unclear.

Methods

We analyzed data from NHANES (National Health and Nutrition Examination Survey) cycles between 2005 and 2018. The composite SDOH score was calculated by summing the weighted scores for each SDOH, categorizing participants into four groups: Q1 (0-1), Q2 (2-3), Q3 (4) and Q4 (≥ 5). Kaplan-Meier survival curves and multivariate Cox proportional hazards models were used to examine the relationship between SDOH and mortality outcome. Restricted cubic spline (RCS) analyses were conducted to explore nonlinear relationships. Subgroup analyses assessed the consistency and robustness of the findings across various demographic a

SUBMITTER: Ma X 

PROVIDER: S-EPMC12016379 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature