Large-scale phenotypic and genomic analysis of <i>Listeria monocytogenes</i> reveals diversity in the sensitivity to quaternary ammonium compounds but not to peracetic acid.

ABSTRACT: Listeria monocytogenes presents a significant concern for the food industry due to its ability to persist in the food processing environment. One of the factors contributing to its persistence is decreased sensitivity to disinfectants. Our objective was to assess the diversity of L. monocytogenes sensitivity to food industry disinfectants by testing the response of 1,671 L. monocytogenes isolates to quaternary ammonium compounds (QACs) and 414 isolates to peracetic acid (PAA) using broth microdilution and growth curve analysis assays, respectively, and to categorize the isolates into sensitive and tolerant. A high phenotype-genotype concordance (95%) regarding tolerance to QACs was obtained by screening the genomes for the presence of QAC tolerance-associated ge

SUBMITTER: Ivanova M 

PROVIDER: S-EPMC12016499 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature