Microbial magnetite oxidation via MtoAB porin-multiheme cytochrome complex in <i>Sideroxydans lithotrophicus</i> ES-1.

ABSTRACT: Most of Earth's iron is mineral-bound, but it is unclear how and to what extent iron-oxidizing microbes can use solid minerals as electron donors. A prime candidate for studying mineral-oxidizing growth and pathways is Sideroxydans lithotrophicus ES-1, a robust, facultative iron oxidizer with multiple possible iron oxidation mechanisms. These include Cyc2 and Mto pathways plus other multiheme cytochromes and cupredoxins, and so we posit that the mechanisms may correspond to different Fe(II) sources. Here, S. lithotrophicus ES-1 was grown on dissolved Fe(II)-citrate and magnetite. S. lithotrophicus ES-1 oxidized all dissolved Fe²⁺ released from magnetite and continued to build biomass when only solid Fe(II) remained, suggesting it can utilize magnetite as a s

SUBMITTER: Keffer JL 

PROVIDER: S-EPMC12016527 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature