Global epidemiology of alcohol-related liver disease, liver cancer, and alcohol use disorder, 2000-2021.

ABSTRACT:

Background/aims

Alcohol represents a leading burden of disease worldwide, including alcohol use disorder (AUD) and alcohol-related liver disease (ALD). We aim to assess the global burden of AUD, ALD, and alcohol-attributable primary liver cancer between 2000-2021.

Methods

We registered the global and regional trends of AUD, ALD, and alcohol-related liver cancer using data from the Global Burden of Disease 2021 Study, the largest and most up-to-date global epidemiology database. We estimated the annual percent change (APC) and its 95% confidence interval (CI) to assess changes in age-standardized rates over time.

Results

In 2021, there were 111.12 million cases of AUD, 3.02 million cases of ALD, and 132,030 cases of alcohol-attributable primary liver cancer. Between 20

SUBMITTER: Danpanichkul P 

PROVIDER: S-EPMC12016609 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature