<i>Toxoplasma gondii</i> and <i>Trypanosoma lewisi</i> Infection in Urban Small Mammals From Cotonou, Benin, With Special Emphasis on Coinfection Patterns.

ABSTRACT: A growing number of studies has highlighted the importance of coinfections in eco-evolutionary processes underlying host-parasite interactions and the resulting epidemiology of zoonotic agents. Small mammals, and particularly rodents, are known to be important reservoirs of many zoonotic pathogens, such as Toxoplasma gondii and Trypanosoma lewisi, that are responsible for toxoplasmosis and atypical trypanosomiasis in humans, respectively. Laboratory experiments on rodent models have shown that primary infection with T. lewisi increases the host sensitivity to other parasites, including T. gondii, following an alteration in the immune response. However, data on potential interactions between these parasites in wild small mammals remain scarce. In this study, we d

SUBMITTER: Etougbetche JR 

PROVIDER: S-EPMC12016718 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature