Carbapenem-Resistant <i>Burkholderia cepacia</i> Complex Isolates Carrying <i>bla</i> _NDM-1 and <i>bla</i> _NDM-5 in Ventilator-Associated Pneumonia Patients and Contaminated Ventilator Tubing.

ABSTRACT: Ventilator-associated pneumonia (VAP) represents an important nosocomial infection, frequently encountered in intensive care unit (ICU) settings which results in prolonged hospitals stays. The nosocomial infections caused by Burkholderia cepacia complex (BCC) bacteria pose a significant challenge in healthcare settings owing to their intrinsic resistance to many antibiotics. This study investigates the antimicrobial susceptibility patterns and mechanisms of carbapenem resistance among BCC bacteria from VAP patients and the ventilator tubing. The blood and respiratory specimens from patients diagnosed with VAP were collected. In addition, the ventilators were also screened for the presence of BCC bacteria. The susceptibility profiling of BCC isolates was performed against the various

SUBMITTER: Saeed M 

PROVIDER: S-EPMC12016991 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature