Prediction of the Potential Host of Peste Des Petits Ruminants Virus by the Least Common Amino Acid Pattern in SLAM Receptor.

ABSTRACT: Peste-des-Petits Ruminants Virus (PPRV) causes a highly contagious and severe infectious disease known as Peste-des-Petits Ruminants (PPR), resulting in significant mortality in both domestic and wild ruminants. An in-depth understanding of the molecular relationship between PPRV and susceptible hosts is essential for the prevention of PPR. The signaling lymphocytic-activation molecule (SLAM) acts as a key receptor in susceptible host species, mediating interactions with PPRV and triggering PPR in ruminants. This study offers an in-depth analysis of PPRV-susceptible host species as well as the identified SLAM amino acid sequences to date. Investigation reveals that nine families-Bovidae, Camelidae, Cervidae, Elephantidae, Suidae, Felidae<

SUBMITTER: Fan X 

PROVIDER: S-EPMC12017033 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature