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Vascular and Myocardial Structure and Function in Adolescents with Type 1 Diabetes: The CARDEA Study.


ABSTRACT:

Introduction

Despite heightened risk of cardiovascular disease (CVD) among individuals with type 1 diabetes, few studies in this population have investigated the development of CVD using early markers in adolescence. We compared risk factors (blood pressure (BP) and dyslipidemia) and early markers of CVD between adolescents with and without type 1 diabetes and explored effect modification by sex.

Methods

Cross-sectional study using data from the CARdiovascular Disease risk in pEdiatric type 1 diAbetes (CARDEA) study. We recruited 100 adolescents with type 1 diabetes at the Sainte-Justine University Hospital Center and 97 adolescents without diabetes (14-18 years). We measured arterial stiffness by carotid-femoral pulse wave velocity, endothelial function by brachial artery f

SUBMITTER: Harnois-Leblanc S 

PROVIDER: S-EPMC12017143 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature