Point-of-care testing of hyponatremia and hypernatremia levels: An optoplasmonic biosensing approach.

ABSTRACT: In the human body, sodium ion (Na+) is the principal extracellular cation and its imbalance in blood or lymph results in either hyponatremia or hypernatremia conditions. Any of these scenarios have fatal effects on a patient's health over time. However, the existing technologies limit quick point-of-care (POC) testing options. To overcome the challenges associated with prompt diagnosis, we proposed a photonic crystal fiber (PCF) based surface plasmon resonance (SPR) sensor for in situ rapid testing of Na+ ion levels in patient's blood samples. A unique PCF sensor with a modified square lattice is engineered to achieve a propagation-controlled core that permits enhanced control over wave guidance resulting in improved sensing performance. Plasmonically active conducting indium tin oxide (IT

SUBMITTER: Hoque AMT 

PROVIDER: S-EPMC12017493 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature