Perceived Stress, Hair Cortisol, and Hair Cortisone in Relation to Appetite-Regulating Hormones in Patients with Obesity.

ABSTRACT:

Introduction

Stress predicts unhealthy eating, obesity, and metabolic deterioration, likely mediated by altered levels of appetite-regulating hormones. Yet, evidence regarding the association between long-term stress and levels of appetite-regulating hormones in humans is lacking.

Methods

We included 65 patients with obesity (44 women) to investigate the cross-sectional association of long-term biological stress (scalp hair cortisol and cortisone) and long-term psychological stress (Perceived Stress Scale) with overnight-fasted serum levels of the hormonal appetite regulators leptin, adiponectin, insulin, pancreatic polypeptide, gastric-inhibitory peptide, peptide tyrosine-tyrosine, cholecystokinin and agouti-related protein, adjusted for age, sex, and body mass index.

Re

SUBMITTER: Kuckuck S 

PROVIDER: S-EPMC12017749 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature