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Psychological distress and suicidal ideation in patients with depressive disorders: the chain mediation of psychological resilience and neuroticism.


ABSTRACT:

Objective

Suicide in depressed patients has become a serious challenge in the field of public health. In-depth analyses of the relationship between psychological distress and suicidal ideation, as well as its intrinsic mechanisms, are of great clinical significance for the prevention of suicide in depressed patients. The objective of this study was twofold: firstly, to explore the intrinsic relationship between psychological distress and suicidal ideation in depth; and secondly, to further investigate the mediating roles of psychological resilience and neuroticism in this relationship.

Methods

In this study, a cross-sectional research design was employed to select 200 patients diagnosed with depression from a mental health centre in Shandong Province. This study utilised the abbreviated version of the Big Five Personality Inventory, the Simplified Scale of Psychological Resilience, the Suicidal Ideation Scale, and the Kessler Psychological Distress Scale to administer questionnaires to patients.

Results

Psychological distress has a direct predictive effect on suicidal ideation. In depressed patients, it also exerts an indirect effect on suicidal ideation via three pathways: the separate mediating effect of psychological resilience, the separate mediating effect of neuroticism, and the chain mediating effect of psychological resilience and neuroticism.

Conclusion

In conclusion, the results of this study elucidate the effect of psychological distress on suicidal ideation in depressed patients and its mechanism of action. Furthermore, they demonstrate the chain-mediated roles of psychological resilience and neuroticism in the relationship between psychological distress and suicidal ideation in depressed patients. Finally, they provide a new perspective for understanding suicidal ideation and preventing suicidal risk in depressed patients. Nevertheless, the present study was only able to measure the correlation between the variables; therefore, it is not yet possible to infer causality. In future, more precise prediction and intervention programmes for suicide risk in depressed patients can be explored in depth through longitudinal or experimental studies, etc.

SUBMITTER: Wang X 

PROVIDER: S-EPMC12018043 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature

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Publications

Psychological distress and suicidal ideation in patients with depressive disorders: the chain mediation of psychological resilience and neuroticism.

Wang Xueqing X   Li Huafang H  

International journal of nursing studies advances 20250408


<h4>Objective</h4>Suicide in depressed patients has become a serious challenge in the field of public health. In-depth analyses of the relationship between psychological distress and suicidal ideation, as well as its intrinsic mechanisms, are of great clinical significance for the prevention of suicide in depressed patients. The objective of this study was twofold: firstly, to explore the intrinsic relationship between psychological distress and suicidal ideation in depth; and secondly, to furth  ...[more]

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