T₁ Relaxation Time for the Prediction of Renal Transplant Dysfunction.

ABSTRACT: Quantitative magnetic resonance imaging (MRI) is emerging as a non-invasive tool to measure tissue scarring in renal allografts. However, whether prolonged T₁ relaxation time results in lower transplant survival rates is unknown. This retrospective cohort study analyzed the capability to predict renal allograft dysfunction based on median T₁ time. Forty-six transplant recipients with non-contrast 1.5T MRI and allograft biopsy were included. The primary endpoint was the eGFR slope over 24 months. T₁ relaxation time correlated significantly with eGFR levels at all follow-up stages. Patients with T₁ relaxation time above the median (T₁ ^high) had a consistent decline in kidney function as compared to the patient group below the

SUBMITTER: Omic H 

PROVIDER: S-EPMC12018245 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature