Non-invasive detection of instantaneous fetal hypoxemia in large animal model of pregnancy.

ABSTRACT: Cardiotocography (CTG) has a high false positive rate for the detection of babies at risk of birth asphyxia. Transabdominal Fetal Pulse Oximetry (TFO) has the potential to supplement CTG by enabling non-invasive measurement of fetal arterial blood oxygen saturation (fSpO₂). Previous attempts at TFO were limited to intermittent measurements using highly specialized and precise instruments. We present a TFO system, utilizing multiple commodity silicon photo-detectors to acquire mixed maternal-fetal PPG signals, for non-invasive and continuous detection of fetal instantaneous normoxia vs. hypoxemia status, relative to a user-specified threshold. Data from controlled de-saturation experiments using pregnant ewes with an in-utero hypoxic lamb model, from a total of n = 8 hypox

SUBMITTER: Qian W 

PROVIDER: S-EPMC12018256 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature