Pan-cancer analysis identified CD248 as a potential target for multiple tumor types.

ABSTRACT:

Objective

Tumors remain a major cause of death worldwide due to late-stage presentation and late diagnosis. Cell therapies have revolutionized the landscape in the precision treatment of tumors. However, there are still many challenges that limit the therapeutic efficacy. Additionally, cancer treatment also entails a major financial burden throughout the entire phase, making it preferable to find a specific biomarker for the early prognosis of the tumor.

Methods

In this study, the role of CD248 in pan-cancer was analyzed through diverse tumor-associated databases, such as the Human Protein Atlas Database, the GEPIA2 Database, the cBioPortal Database, the TIMER Database, the STRING tool, and so on. In addition, CD248 mRNA and protein levels were assessed in a series of head a

SUBMITTER: Guo L 

PROVIDER: S-EPMC12018388 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature