Association between maternal cancer and the incidence of cancer in offspring.

ABSTRACT: Despite the growing population of young cancer survivors of reproductive age, the risk of cancer in offspring born to female cancer survivors has yielded inconsistent results. Therefore, this study aimed to investigate the risk of cancer among the offspring of female cancer survivors by maternal age at delivery, maternal age at cancer diagnosis, maternal cancer type, and the time interval between cancer diagnosis and pregnancy. Using nationwide retrospective mother-child linked data from the Korean National Health Insurance Service, we included the first child (N = 8031) of female cancer survivors aged < 40 years after excluding thyroid cancer survivors and matched controls (N = 24,093) between 2005 and 2019. Subgroup analysis was performed according to maternal age at delivery, maternal a

SUBMITTER: Jeong SM 

PROVIDER: S-EPMC12018610 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature