In vitro Evaluation of the Nematicidal Efficacy of Quercetin on Adult Toxocara canis.

ABSTRACT:

Purpose

Toxocara canis is a globally distributed zoonotic parasite found in dogs' intestines, leading to various pathological damages, particularly to the intestinal flora. The larval stage causes human toxocariasis, especially in children, and may result in neurological disorders and blindness. Quercetin is a flavonoid with strong secondary metabolites and possesses medicinal advantages and antiparasitic qualities.

Methods

The assay involved  four groups, each of  10 young adult T. canis; Group I was incubated in concentrations of an ethanolic extract of quercetin, Group II in albendazole (0.2 mM/ml) (+ve control), Group III in RPMI 1640 medium with ethanol (control), and Group IV in RPMI 1640 medium only (-ve control). The potential action of quercetin against adult T. can

SUBMITTER: Elmahy RA 

PROVIDER: S-EPMC12018618 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature