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ABSTRACT: Objective
To explore why older men awaken to urinate within 3 h after falling asleep, we examined diuretic and urine storage states associated with the first void after falling asleep.Methods
We enrolled 102 male patients, 50 years or older, hospitalized for prostate biopsy between November 2021 and September 2023. Patients were grouped based on their first undisturbed sleep period (FUSP): FUSP < 3 h or FUSP ≥ 3 h. A 24-h frequency-volume chart (FVC) was recorded. Urinary sodium, creatinine, and osmolality were measured from the first urine after sleep and upon waking. Free water clearance (FWC) and sodium clearance (SC) of the first urine after sleep were recorded. The urine storage state was calculated as the ratio of urine volume at first nocturnal voiding to the maximum
SUBMITTER: Akashi Y
PROVIDER: S-EPMC12018642 | biostudies-literature | 2025 Apr
REPOSITORIES: biostudies-literature