Early Albumin Administration in Veno-Arterial Extracorporeal Membrane Oxygenation.

ABSTRACT:

Background

The clinical outcome and fluid balance of patients with veno-arterial extracorporeal membrane oxygenation (VA ECMO) or after extracorporeal cardiopulmonary resuscitation (eCPR) may be improved by addressing the high fluid demand with an early albumin administration.

Methods

In this prospective observational study, patients supported with VA ECMO or eCPR received early albumin administration (25 g/L) to prime the VA ECMO system. These patients were compared to patients who received a regimen based solely on balanced crystalloids (crystalloid group) or a regimen based on a 1:4 volume mixture of albumin (10 g/L) and balanced crystalloids (albumin group).

Results

660 VA ECMO patients (66.4% eCPR) treated between January 2017 and June 2021 were analyzed, whereby

SUBMITTER: Wengenmayer T 

PROVIDER: S-EPMC12019102 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature